Calcaterra V, Tornese G, Zuccotti G, Staiano A, Cherubini V, Gaudino R, Fazzi EM, Barbi E, Chiarelli F, Corsello G, Esposito SMR, Ferrara P, Iughetti L, Laforgia N, Maghnie M, Marseglia G, Perilongo G, Pettoello-Mantovani M, Ruggieri M, Russo G, Salerno M, Striano P, Valerio G, Wasniewska M, Italian Academy of Pediatrics, Italian Society of Pediatrics (2024) Adolescent gender dysphoria management: position paper from the Italian Academy of Pediatrics, the Italian Society of Pediatrics, the Italian Society for Pediatric Endocrinology and Diabetes, the Italian Society of Adolescent Medicine and the Italian Society of Child and Adolescent Neuropsychiatry
re-analyzed data from six previously published studies and focused on indexing glutamatergic and GABAergic neurotransmission in the DLPFC of 57 schizophrenia and HV matched pairs [81]
Figure 3 specifically illustrates these associations for weight change
The patients receiving tirzepatide also showed improvements including body weight, liver blood markers, and the safety profile was confirmed as similar to what was seen in previous clinical trials