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Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders

In contrast, the NLRP3 inflammasome is a key mediator of the neuroinflammation process [9]

Singh, M., Singh, G., Kanwar, A

However, because the multistep chemical reaction of protein nitration by peroxynitrite requires the involvement of a metal ion such as ferrous iron [79], the role of iron in APAP hepatotoxicity is independent of the Fenton reaction under normal conditions [80]