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70 These changes reduce short-chain fatty acid (SCFA) production and increase secondary bile acid formation, both of which compromise gut barrier integrity

Pinilla-Gonzlez V, Rojas-Sol C, Gmez-Hevia F, Gonzlez-Fernndez T, Cereceda-Cornejo A, Chichiarelli S, Saso L, Rodrigo R

Even in long-term studies where subjects used PT-141 multiple times weekly for months, no pigmentation changes were documented

Use of Chelation Agents: If a subject is undergoing chelation therapy to remove heavy metals from the body, using GHK-Cu is counterproductive and potentially confusing for the system