semaglutide and the heart Potential action mechanisms of in phenotype of Weight loss drug's heart benefits

GLP-1 is released eating and lasts only about 1-2 minutes before an enzyme called DPP-4 breaks it down

Foods that contain large amounts of histamine (see list below), or those that inhibit DAO activity (eg, alcohol), can also worsen symptoms of histamine intolerance

The current recommendation: do not prescribe Wegovy to a child under 12 outside of a clinical trial or a carefully documented, individually justified off-label protocol with enhanced safety monitoring, and check ClinicalTrials.gov (identifier search: semaglutide AND pediatric) for new enrollment opportunities before initiating off-label therapy

If you notice any changes, keep an eye on them to see if they get worse