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Gene therapy studies using HGF have demonstrated beneficial effects in animal models of amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and cerebral ischemia, with HGF treatment promoting neurite extension, increasing synaptogenesis, and enhancing functional recovery

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Awareness by surgical pathologists of the wide morphological spectrum of these tumors and their development in the context of tumor-predisposing syndromes is crucial for providing correct prognostic information and planning the clinical/radiological follow-up of patients