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doi: 10.1053/j.gastro.2016.01.032 48
Mitochondria is a cellular organelle often referred to the "powerhouse" of the cell, regulating a range of functions from energy generation, metabolism and cell survival
moreover, in the context of immunotherapy and targeted agents there is compelling translational evidence primarily from murine models and observational cohorts in other cancers that specific taxa enhance antitumour immune responses and predict checkpoint inhibitor efficacy, suggesting analogous potential in subsets of breast cancer patients, particularly those receiving immunomodulatory regimens (177)
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