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By selectively activating melanocortin receptors, Melanotan 2 influences melanin production, UV response, and other pigmentation-related cellular processes

take at night or reduce dose) Flushing or facial warmth Appetite suppression (desired in some cases) Fatigue or dizziness (rare) Less Common: Darkening of freckles or moles (especially in fair-skinned users) Hyperpigmentation of scars or birthmarks Spontaneous erections (especially in males at higher doses) Contraindications: History of melanoma or atypical nevi Active hormone-sensitive cancers Uncontrolled autoimmune flares without provider oversight Clinical Case Examples Case 1: Safe Tanning and Photosensitivity A 30-year-old female with light skin and lupus-associated photosensitivity followed the tanning protocol

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Acknowledgements We thank Daniel Paul Sampey for the English revision