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High concentrations of NOX1 and NCF2 can disrupt oxidativeantioxidative balance, leading to the release of reactive oxygen and nitrogen species outside of the cell along with NETs

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A single administration of 8 at 42 d.p.i (200 mg/kg i.p.) resulted in a 19% and 7% decrease in worm and egg burdens, respectively

5.6 Vasculature: vascular reactivity and blood pressure control Vascular smooth muscle (VSM) is essential for regulating vascular tone, blood pressure, and vessel remodeling