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All ASO sequences, modification patterns and modified versions thereof can be found in Supplementary Table 3

It's a field where a single microgram can be the difference between a breakthrough and a null result

1 Introduction Glucoraphanin (GRP) is a naturally occurring sulfur-containing compound mainly produced by cruciferous plants such as cauliflower, broccoli, radish, cabbage, arugula, kale, bok choy, Brussels sprouts, collards, and watercress

Reduction of mRNA expression of matrix molecules, including collagen, in elderly animals was observed in multiple studies [18,19,20,21], and similar down-regulation of cytoskeletal genes, such as actin, was also associated with aging [22,23]