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Role of extrinsic apoptotic signaling pathway during definitive erythropoiesis in normal patients and in patients with -thalassemia

Upon -KG insufficiency or treatment by -KG competitors (succinate and ITA), lower TET activity reduces YBX1 transcription and prevents AMPK1 translation

CytoFLEX S flow cytometer (Brea, CA, USA) was used to collect flow cytometry data

Effect of Ang II on medullary RBF Ang II elicits a paradoxical medullary vasodilatation in normotensive animals, mediated by a secondary activation of vasodilator paracrine agents such as prostaglandins, kinins and NO, rather than to a direct action via AT 2 receptors