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Ramp-Up Strategy for Sensitive Stomachs If you are coming off a magnesium form that caused diarrhea, ramping up slowly helps your gut adjust: Week 1: 100 to 150 mg of elemental magnesium with the evening meal Week 2: 200 mg with the evening meal Week 3: 250 to 300 mg, possibly split into 2 doses Week 4 forward: reach your target dose based on goal Most people do not need this approach with glycinate, but it is useful if you have had repeated GI issues with magnesium in the past