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I am relieved with the findings of this study that there does not appear to be any increased cancer signals, Wolver said, but I am also not dismayed that there was no reduction in the development of cancer or metastases, because I think we just didnt have a long enough time.

After eight weeks, leg heaviness was reported to be reduced by 60.4% in the Pycnogenol group compared to a reduction of 12.6% in the placebo group

However, most cases occurred in patients with a shock state and/or tissue hypoxia or in the presence of several other predisposing conditions like impaired renal function and heart failure (Table 10.3)

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