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DOI:10.1002/hep.22560 82

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Furthermore, no adverse events have been found following physical activity programs in patients with PWS, although continuous supervision and support from experienced personnel is required

These results are consistent with the major features of hind-limb suspension-related phenotypes of skeletal muscles as an index of anti-gravity muscle atrophy 66 , thus assuring that the experimental design including the mouse age and muscle-disuse period (in vivo assay time-point) were appropriate to the conclusion that 3-days LASSS oral-administration prevents tyrosine-residue nitration of extracellular HGF (Y198) during 5-days muscle disuse