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This pathway primarily occurs in the liver and kidney and involves four key enzymes: Trimethyllysine Hydroxylase (TMLH), Hydroxytrimethyllysine Aldolase (HTMLA), Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH), and -Butyrobetaine Hydroxylase (BBOX)

More detailed geographic and socioeconomic information would strengthen the analysis of disparities and should be incorporated in future research

The authors stressed, however, that more studies are needed to confirm a link between the blockbuster drugs and vision problems