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When compared to the other analogs in the study, the one that showed the best activity has a 3hydroxy group next to the 4carboxyl, which may have influenced the increase in potency, when compared to the other compounds in the study which were more than 27 times less potent (when compared to the second most potent in the study, the others being even less potent)

Neutral pH is generally safest for most peptides, which is convenient because bacteriostatic water has a near-neutral pH

A 12-week controlled facial study demonstrated a 55.8% reduction in wrinkle volume compared to a control group

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