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Indeed, four out of five hydroxyl groups of quercetin can be glucuronidated by UDP-glucuronosyltransferase, forming its major metabolites: quercetin-3-glucuronide, 3'-methylquercetin-3-glucuronide, and quercetin-3'-sulfate (112)

To put it in context, nicotinamide has shown signs of liver toxicity only at doses around 3,000 mg per day or higher