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Numerous mitotic figures are present

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Key cytokines, such as IL-6 and IL-22, along with regulatory immune cells, including Th17, Treg, and Breg cells, play significant roles in modulating the inflammatory response and maintaining mucosal integrity

Consequently, future therapeutic protocols designed to sequentially or simultaneously trigger both death routes must critically interrogate whether the inflammation ignited by ferroptosis can effectively neutralize the immunosuppression orchestrated by cuproptosis