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In the human skeletal muscle (pH 7.1), which lacks carnosinase-1, the degradation of carnosine by carnosinase-2 is very limited, because its optimal pH 9.5 is much greater than the intracellular pH and its V max is 30 times lower than that of carnosinase activity in the human kidneys (Lenney et al

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In addition, Hsa_circ_0054633 suppression promotes -cell proliferation and facilitates insulin secretion through inhibiting caspase-8 expression by sponging miR-409-3p