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NICE did update the CKS (Clinical Knowledge Summary) in March 2024 Scenario: Management Anaemia B12 and folate deficiency They made a page specifically for patients and actively connected with the Pernicious Anaemia Society as a source of expertise for patients to contact Information for the public: Vitamin B12 deficiency in over 16s: diagnosis and management What are others doing

General Safety Adults tolerate it well for both subcutaneous and intramuscular injection

(By contrast, plain Sterile Water for Injection has no preservative and must be used as a single dose.) The product label explicitly notes that the vial may be made to dilute or dissolve drugs for injection and is designed for repeated withdrawals

The best method for you depends on your specific needs and comfort level