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Heres how they affect the body: Slow down digestion, making you feel full for longer Reduce appetite by acting on the brains hunger centers Help regulate blood sugar levels May increase energy expenditure The Impact on Healthcare Costs Recent statistics show that GLP-1 drugs are having a significant impact on healthcare costs: According to a 2023 report by the American Diabetes Association, GLP-1 drugs could potentially save $40 billion annually in U.S

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SP preferentially binds to NK1R and NK1R is expressed in many of the same brain regions as SP (Mantyh et al., 1984