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The most frequently reported side effects in this study were mild to moderate nausea, diarrhea, vomiting, and constipation

doi: 10.1002/iub.1646 2 Adeva-AndanyM

Dehydration, blood sugar fluctuations, and the physiological stress of metabolic adaptation can all trigger headaches

In a pilot trial evaluating 104 amnestic MCI and early-stage AD patients, 20 IU and 40 IU doses of intranasal insulin improved Alzheimers Disease Assessment Scale-Cognitive subscale (ADAS-Cog 12) scores compared to placebo-treated patients, with improvements in delayed recall observed 2 months following cessation of treatment in the 20 IU group