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Consequently, GLP-1, secreted by the EEC-L cells, plays a crucial role in gut barrier protection by diminishing mucosal inflammation and enhancing mucin synthesis 54

There is substantial evidence indicating that AKT signaling is able to phosphorylate STAT3 protein although sometimes there is no specification on whether AKT directly phosphorylated STAT3 or whether the activation was induced indirectly through the activation of mTOR or PKM2 (see below)

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There were no language restrictions for the literature search, and any additional study in the reference lists of identified trials or reviews was searched