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Additional Benefits: Supports cardiovascular health

thus, elevated ROS or RNS in patients could lead to non-enzymatic decomposition of 5-HT in vivo

Patients with RA should continue evidence-based DMARD therapy as recommended by the American College of Rheumatology, while any GLP-1 use should be reserved for approved indications such as diabetes or weight management under appropriate medical supervision

Real-world persistence is low: about half discontinue within a year and roughly three-quarters within two years , often due to cost or side effectsraising the risk of rebound weight and lost health gains (Scientific American on discontinuation rates)