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*Correspondence: Giulio Bonomo, [email protected] These authors have contributed equally to this work ORCID: Giulio Bonomo, orcid.org/0000-0002-4749-7929 This article was submitted to Neuro-Oncology and Neurosurgical Oncology, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Receptor sensitisation: Some research suggests that alternating between different secretagogue mechanisms may prevent receptor downregulation compared to chronic stimulation of a single pathway