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The main symptoms these subjects experienced involved the skin, gastrointestinal tract, respiratory system, and eyes, which were also improved by following a low-histamine diet

Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

The hormonal fluctuations that occur during perimenopause can lead to thinning hair and increased shedding

These liver issues may potentially be the initial signs of a carnitine deficit