semaglutide common name | C187H291N45O59 | CID 56843331 Rybelsus (semaglutide): Uses, Side Effects,

doi:10.1001/jama.2022.0078 89

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The impact of GLP-1 RAs on lipid synthesis and oxidation in the liver, resulting in decreased inflammation and fibrosis, has led to studies evaluating their potential for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction-associated steatohepatitis (MASH), and inflammatory bowel disease (IBD), and the prevention of hepatobiliary and other gastrointestinal (GI) cancers [1,5]

PTH (184) and insulin were determined using ELISA kits from ALPCO Diagnostics, and the HOMA-IR index was calculated (42)