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Different strategies were used to improve the peptide half-life including sequence modifications (exenatide, lixisenatide) 36,37 , conjugation to molecules with propensity to bind albumin (liraglutide, semaglutide) 36,37 , fusion to large proteins (albiglutide, dulaglutide, efpeglenatide) 36,37 , side chain cross linking 38,39 , and -residue replacement 40,41,42 (Fig

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Depending on your individual circumstances, your GP or diabetes team may advise: Self-monitoring of blood glucose (SMBG) using a finger-prick glucometer, particularly before meals, after exercise, and before driving Continuous glucose monitoring (CGM) or flash glucose monitoring , which provide real-time or on-demand glucose readings and can alert users to falling levels