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IUBMB Life 70:519528 Omene CO, Wu J, Frenkel K (2012) Caffeic acid phenethyl ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells
Glutathione supports Phase II detoxification pathways that handle these compounds efficiently
data using a STRING database
Peroxidation of membrane results in huge compromise of the structural and functional integrity of the cell characterized by altered membrane permeability,17 dysfunctionality of membrane receptors,18 decreased activity of membrane-bound enzymes19 and increased membrane rigidity which decreases membrane fluidity.20 The possibility of free radicals directly attacking membrane proteins, induce lipid-lipid, lipid-protein and protein-protein cross linking also exist.21 Peroxynitrate (ONOO), a powerful oxidant is formed when O2 reacts with nitric oxide radical (NO) in the presence of arginine and NADPH-Oxidase enzyme
