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Risk Tolerance and Side Effects Tesamorelin, due to its strong GH-releasing effect, may lead to: Joint discomfort Swelling or redness at the injection site Elevated blood glucose Sermorelin, by contrast, typically causes fewer side effects such as: Mild headaches Injection site irritation Occasional nausea or dizziness Those with sensitive systems or pre-existing conditions may benefit more from Sermorelins gentler action

Patients taking insulin or sulfonylureas should monitor blood glucose more frequently and work with their healthcare provider to adjust these medications as needed to prevent hypoglycemia

That was part of the reason why Noom decided to start selling small doses of compounded versions of Wegovy, the prescription medication developed by Novo Nordisk

Note that TB-500 and TB4 Frag are sold as wellness products and not as an FDA-approved therapeutic drug in the US