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Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade

Iron decreased in the first and second groups only

Aug 2020;146(2):367-376 e3

The complexity of glutamine metabolism means that the development of a one-size fits all wonder drug against all glutamine-dependent tumours is unlikely