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Our work suggests that reno-protective strategies could potentially lower circulating TMAO and therefore preserve kidney function in individuals with high circulating TMAO in the presence of risk factors known to increase TGF-1 signaling (i.e., hypertension and T2D 58 )

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The patients who received 5 mg were found to have 0.70% in HbA1c level versus 0.72% in the group that received 15 mg [25]