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Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: potential targets for the development of new therapeutic agents

Future studies integrating cell-type specific, regional and temporal analyses of oxysterol signaling will be essential to harness this pathway for therapeutic benefit and to advance our understanding of CNS vulnerability and resilience

Analytical technology development and targeted chelation therapy Further development of in situ analytical techniques is required to characterize the chemical speciation and subcellular distribution of accumulated platinum, which is the basis for accurate toxicity assessment and targeted intervention