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On the contrary, multidrug resistance-associated proteins MRP1, MPR4, and MPR5 are not only involved in the uptake of antimalarial drugs but also in the efflux of some metabolites (e.g., oxidized glutathione conjugates and cyclic nucleotides) (Figure 1)

Cha et al

Sukhanov S, Higashi Y, Shai SY, Vaughn C, Mohler J, Li Y, Song YH, Titterington J, Delafontaine P

The unique formulation includes critical cofactors that many people are missing: selenium to activate your glutathione peroxidase (GPX) enzyme, riboflavin to recycle used glutathione via your glutathione reductase (GSR) enzyme, molybdenum to support your sulfite oxidase (SUOX) enzyme and prevent the uncomfortable side effects some people experience from glutathione