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As non-interventional approaches are often frustrating and bariatric surgery is an effective yet invasive procedure, GLP-1-RAs present an attractive treatment option in patients with IIH (pwIIH)

These pathways operate through several mechanisms: The primary signaling cascade involves dual pathways: (1) Gs-mediated activation of adenylyl cyclase leading to increased cAMP production and subsequent activation of protein kinase A (PKA) and exchange protein activated by cAMP (Epac), and (2) PI3K/Akt pathway activation [4]

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