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A.et al (2019)

Clinical importance of folate cycle inhibitors and synthesis of dTMP Synthesis of dTMP for DNA synthesis is the rate-limiting step for the replication process, and therefore disruption of this conversion is very effective at reducing cellular proliferation

Endogenous GH secretion is already at its lifetime peak during mid-puberty, reaching pulse amplitudes roughly double those seen in healthy adults, driven by rising sex steroids [5]