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Despite the strength in the large cumulative sample size and compilation of data from the statistically robust design of RCTs, one of the major limitations of meta-analysis studies for retinopathy is the lack of standardization in reporting and detecting retinopathy across the included trials

These findings highlight the importance of selecting the most appropriate GLP-1 agonist for individual needs and goals

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For example, too much vitamin B12 might cause diarrhoea or skin rashes, overdose of folic acid may cause nausea or bloating, high doses of niacinamide might lead to skin flushing or itching, and excess vitamin C could lead to diarrhea or abdominal cramps