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Ferroptosis results from increased lipid peroxidation caused by GPX4 deficiency ( 3 Ferroptosis in the development of ARDS 3.1 Alveolar epithelial cell damage The distinct functions of ferroptosis in alveolar type I (AT1) and type II (AT2) epithelial cells have been brought to light by recent research, offering information about possible treatment targets ( AT1 cells regulate gas exchange and preserve alveolar shape ( Ferroptosis in alveolar epithelial cells is caused by a number of important processes and regulatory variables
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