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Description

Myth: You can stop GLP-1 medications abruptly with no effects

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Some patients experience constipation during this phase due to slowed gastrointestinal motility

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Indeed, it has been estimated that just 10-15% of the secreted GLP-1(7-36) NH2 reaches the systemic circulation (117), with some authors reporting meager peripheral meal-induced changes in both healthy and diabetic people (118)

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More extensive human trials are needed to confirm these preclinical observations, establish optimal dosing, and fully understand its safety profile

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