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In larger areas of lost volume, some patients turn to plastic surgery, where excess fat can be removed from ones stomach or thighs and be injected into the butt to restore volume and shape

In contrast, CNS, but not vagal, GLP-1Rs were required for a complete anorectic response to the long-acting GLP-1R agonist liraglutide and the anorectic and weight loss effects of chronic liraglutide treatment