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Its known that 22 splice variants of hTERT exist (Plyasova and Zhdanov 2021) however, only the full-length variant codes for the fully active telomerase enzyme and some variants can act in a dominant negative way to inhibit telomerase activity

340 Most APL patients express the special fusion protein PML-RAR, which comprises PML zinc finger protein sequences and retinoic acid receptor sequences

Moreover, the levels of vascular VEGF, angiopoietin, and platelet-derived growth factor (PDGF)-B&D were restored

Vitamin C reconfigures the gut microbiota, improves the intestinal environment, reduces inflammatory responses and oxidative stress in the paraventricular nucleus of the hypothalamus, thereby weakening sympathetic nervous activity in hypertensive rats and lowering blood pressure (83)