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Furthermore, L-carnitine as a potent antioxidant can decrease oxidation of purine and pyrimidine bases, breakage of DNA single and double strands, DNA fragmentation and protamine deficiency and maintain DNA integrity during cryopreservation by ROS reduction (78)

We further investigated the extent of phosphorylation of CREB, the major downstream effector of BDNF [51, 52], as marker of BDNF signalling

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