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The cleared lysate (35 ml) supplemented with 700 l of 2 M imidazole (final concentration 40 mM) was mixed with 1.5 ml Ni-NTA beads equilibrated with 10 ml lysis buffer and incubated at 4 C for 2.5 h with gentle rotation

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And, while new manufacturing capacity is planned, the timelines to bring regulated facilities online are significant

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Its primary role is immune regulation, particularly within epithelial and mucosal tissues

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