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Rapid glucose reduction associated with GLP-1 therapy has been linked to worsening of diabetic retinopathy in some studies, particularly the SUSTAIN-6 trial with semaglutide

The controversial role of human gut Lachnospiraceae

GLP1/GIP and the triple-agonist, promoting a sustained and significant decrease in body weight (8%), a marked reduction in fat tissue (40%) and food intake, as well as an improvement in glucose metabolism (Fig