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In addition, studies have reported that abnormal lipid accumulation in the TME leads to decreased antigen presentation ability of DCs and anti-tumor ability of T cells (88)

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Protease family S9 is divided into 4 subfamilies: S9A (type prolyl oligopeptidase), S9B (DPP4), S9C (acylaminoacyl peptidase), and S9D (glutamyl endopeptidase)