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doi:10.1016/0014-5793(87)81495-3

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To answer that, we need to look at the key factors such as absorption, duration, safety, practicability and cost

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1 However, oral administration of protein/peptide therapeutics has proven difficult due to the harsh conditions of the upper gastrointestinal tract and poor absorption rates in the small intestine

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In Summary Liraglutide, semaglutide, and tirzepatide represent a genuine advance in the medical management of obesity and type 2 diabetes

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