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6 This deficiency is particularly concerning for GLP-1 users who may experience gastrointestinal side effects like diarrhea (5-36% of semaglutide users) and constipation (5-37% of semaglutide users)

We also removed the cost report data of 6 hospitals because these hospitals had cost report data that were not complete (missing aggregate OPPS payments, missing aggregate cost data, or missing both), so that all cost reports in the study would have both the payment and cost data necessary to calculate a PCR for each hospital, leading to an analytic file of 3,341 hospitals with cost report data

The moral of the story is that semaglutide may improve leptin sensitivity by regulating leptin and preventing resistance to this powerful satiety hormone