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For weight management , NICE technology appraisal guidance supports semaglutide 2.4 mg (Wegovy) for adults with at least one weight-related comorbidity and a BMI 35 kg/m (or 30 kg/m in exceptional circumstances), as part of a specialist weight management service

Am J Clin Nutr , 122 (1), 174-184

The drug you choose may depend on the condition you are treating and whether you are comforting self-injecting medication

Some research describes a theoretical health risk of probiotics in immunocompromised people , in particular.43 In 2013, for example, a case report described a 17-year-old with universal ulcerative colitis developing sepsis after taking the probiotic Lactobacillus rhamnosus .44 L