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Any weight loss observed in studies is modest at best and should not be considered a substitute for evidence-based lifestyle interventions

Sensitivity analyses were, therefore, performed to assess the robustness of the base case findings

The vagus nerve in the neuro-immune dialogue: from preclinical studies to bioelectronic medicine Studies initiated about 20 years ago substantially broadened knowledge about the vagus nerve by revealing the role of this nerve in the regulation of immunity and inflammation (Borovikova et al., 2000

In the total population, the differences with semaglutide 2.4 mg versus comparators ranged from 0.40% (CrI 4.22, 3.46) for phentermine 15 mg/topiramate 92 mg to 9.36% (CrI 12.06, 6.62) for placebo/control