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At nine and twelve months the distribution continued to shift modestly, with 33% still showing further improvement, and 20% and 21% worse than their pre-GLP-1 level, respectively

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Together these four actions steady blood sugar and support gradual weight loss, which is how GLP-1 drugs work at a practical level

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Clinical Trial Comparisons Semaglutide (STEP program): The STEP 1 trial demonstrated a mean weight reduction of approximately 14.9% from baseline over 68 weeks with semaglutide 2.4mg weekly

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