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Mechano Growth Factor (MGF) is produced by skeletal muscle in response to mechanical loading, eccentric exercise, or injury through alternative splicing at exon 5 of the IGF-1 gene, generating a C-terminal extension peptide (the Ec peptide) that is unique to MGF and absent from systemic IGF-1

Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats

GI side effects affect 10% to 40% of GLP-1 users, particularly during the first few weeks and during each dose escalation

Enhances bone healing: Accelerated bone formation and improved graft healing in rat anterior cruciate ligament reconstruction model 2